Good cholesterol 'can turn nasty and clog arteries'
"Good", or HDL, cholesterol commonly assists to hold arteries clear and is good for heart wellbeing.
But the group at the Cleveland Clinic showed it can become abnormal and lead to impeded blood vessels.
They say persons should still consume healthily, but that the good cholesterol story is a more complex tale than previously considered.
Low-density lipoprotein (LDL) cholesterol is awful" because it is deposited in the partitions of arteries and determinants hard plaques to construct up that can cause blockages, producing in heart attacks and stroke.
High-density lipoprotein (HDL) cholesterol is "good" because the cholesterol is rather than transported to the liver.
The evidence shows that having a high ratio of good to awful cholesterol is good for wellbeing.
However, investigators at the Cleveland Clinic say trials directed at boosting grades of HDL have "not been thriving" and the role of good cholesterol is clearly more complicated.
'Exact chemical change'
In their study, released in the journal Nature surgery, they displayed how HDL cholesterol could become abnormal.
One of the investigators, Dr Stanley Hazen, said HDL cholesterol was being changed in the partitions of the artery.
Small amounts of the abnormal HDL seep back into the bloodstream and this can be detected.
checks on 627 patients displayed that levels of abnormal HDL in the body-fluid could be utilised to forecast the risk of cardiovascular disease.
Dr Hazen supplemented: "This facts and figures does not change the note of eat healthily."
rather than, he said the findings would be utilised to evolve new checks for abnormal HDL cholesterol and study on pharmaceuticals to help impede its formation.
Dr Shannon Amoils, a senior study adviser for the British Heart Foundation, said: "Although conventionally we believe of HDL as 'good' cholesterol, the reality is much more convoluted.
"We now understand that under certain situation HDL can become dysfunctional, potentially assisting to clog impeded arteries.
"This interesting research pins down the accurate chemical change that determinants the 'good' HDL cholesterol to become awful.
"This information could permit researchers to supervise coronary artery infection more nearly or even goal the 'bad' HDL with drugs."
But the group at the Cleveland Clinic showed it can become abnormal and lead to impeded blood vessels.
They say persons should still consume healthily, but that the good cholesterol story is a more complex tale than previously considered.
Low-density lipoprotein (LDL) cholesterol is awful" because it is deposited in the partitions of arteries and determinants hard plaques to construct up that can cause blockages, producing in heart attacks and stroke.
High-density lipoprotein (HDL) cholesterol is "good" because the cholesterol is rather than transported to the liver.
The evidence shows that having a high ratio of good to awful cholesterol is good for wellbeing.
However, investigators at the Cleveland Clinic say trials directed at boosting grades of HDL have "not been thriving" and the role of good cholesterol is clearly more complicated.
'Exact chemical change'
In their study, released in the journal Nature surgery, they displayed how HDL cholesterol could become abnormal.
One of the investigators, Dr Stanley Hazen, said HDL cholesterol was being changed in the partitions of the artery.
Small amounts of the abnormal HDL seep back into the bloodstream and this can be detected.
checks on 627 patients displayed that levels of abnormal HDL in the body-fluid could be utilised to forecast the risk of cardiovascular disease.
Dr Hazen supplemented: "This facts and figures does not change the note of eat healthily."
rather than, he said the findings would be utilised to evolve new checks for abnormal HDL cholesterol and study on pharmaceuticals to help impede its formation.
Dr Shannon Amoils, a senior study adviser for the British Heart Foundation, said: "Although conventionally we believe of HDL as 'good' cholesterol, the reality is much more convoluted.
"We now understand that under certain situation HDL can become dysfunctional, potentially assisting to clog impeded arteries.
"This interesting research pins down the accurate chemical change that determinants the 'good' HDL cholesterol to become awful.
"This information could permit researchers to supervise coronary artery infection more nearly or even goal the 'bad' HDL with drugs."
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